Autophagy Regulates Expression of Argonaute 2, a Critical Regulator of the MicroRNA Silencing Pathway

Genome-wide association studies have implicated autophagy in Crohn’s Disease (CD) pathogenesis. The functional relevance of autophagy in CD remains unknown. I hypothesized that autophagy is involved in microRNA silencing, another process implicated in CD pathogenesis. MicroRNAs are short non-coding...

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Bibliographic Details
Main Author: Sibony, Michal
Other Authors: Jones, Nicola L.
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/42408