Preclinical Modeling of Treatment-induced Impulsivity in Parkinson's Disease
Dopamine agonist therapy and deep brain stimulation (DBS) are both linked to increased impulsivity in Parkinson’s disease (PD), but the underlying mechanisms remain unclear. We trained intact and PD-like rats on a rat gambling task (rGT) measuring impulsive choice and premature responding. Animals...
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Language: | en_ca |
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2013
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Online Access: | http://hdl.handle.net/1807/42665 |