Investigating the Role of Autophagy in Intracellular Apolipoprotein B Traffic and Very-low-density-lipoprotein Assembly and Secretion
Apolipoprotein B (apoB) is the main protein of very-low-density lipoprotein (VLDL). As apoB is translated and moves through the secretory pathway, lipids from cytoplasmic lipid droplets (LDs) are added to form VLDL particles. Without adequate lipid availability, apoB is misfolded and undergoes prote...
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Language: | en_ca |
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2013
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Online Access: | http://hdl.handle.net/1807/42743 |