Exacerbated Cardiac Fibrosis in Apelin-deficient Mice post Myocardial Infarction is Associated with Vimentin and MicroRNA-378
The Apelin-APJ system is transiently up-regulated in murine models of cardiac dysfunction. We have previously shown that Apelin-deficient mice subjected to aortic constriction suffer from severe fibrosis. In turn, we hypothesized that Apelin deficiency will also exaggerate the fibrosis phenotype pos...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/42895 |