Controlled Conjugation of [Cu,Zn] Superoxide Dismutase: An Active Tetramer
While the catalytically powerful [Cu,Zn] superoxide dismutase (SOD1) possesses great potential as a therapeutic, unfavorable properties in circulation limit its use in clinical medicine. The small, water soluble dimer is rapidly excreted by the kidney. Previous initiatives have been used to increase...
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Language: | en_ca |
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2013
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Online Access: | http://hdl.handle.net/1807/42934 |