Controlled Conjugation of [Cu,Zn] Superoxide Dismutase: An Active Tetramer

While the catalytically powerful [Cu,Zn] superoxide dismutase (SOD1) possesses great potential as a therapeutic, unfavorable properties in circulation limit its use in clinical medicine. The small, water soluble dimer is rapidly excreted by the kidney. Previous initiatives have been used to increase...

Full description

Bibliographic Details
Main Author: Siren, Erika
Other Authors: Kluger, Ronald
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/42934