Osteogenic Differentiation from Mouse Embryonic Stem Cells and the Role of Calreticulin
Calreticulin, an endoplasmic reticulum (ER)-resident protein, is a calcium buffering chaperone. In this study, with an optimized differentiation protocol from mouse R1 ES cells, we demonstrate a novel role of calreticulin in osteogenic commitment and differentiation. To enhance the efficacy of the m...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/43356 |