Properdin Binds Pseudomnas aeruginosa and is Required for Neutrophil Extracellular Trap Mediated Activation of Complement Alternative Pathway

Neutrophils play an important, yet poorly understood role, in complement mediated pathologies. Here we identified that neutrophils contain key components from the complement alternative pathway: properdin (CFP), complement component 3 (C3), complement factor B (CFB), and complement factor H (CFH). A...

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Bibliographic Details
Main Author: Yuen, Joshua
Other Authors: Licht, Christoph
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/43357