Characterization of Kallikrein-related Peptidase-8 in Normal Human Epidermis and Psoriasis

Kallikrein-8 (KLK8) is a relatively-uncharacterized epidermal protease. Although proposed to regulate wound-healing and barrier repair in KLK8-deficient mouse skin, KLK8-catalytic activity was never demonstrated in human epidermis and its regulators and targets remain largely unknown. KLK8 overexpre...

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Bibliographic Details
Main Author: Eissa, Azza
Other Authors: Diamandis, Eleftherios P.
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/43602