The Mechanism of a BMP-Driven Mesenchymal-to-Epithelial Transition in the Reprogramming of Induced Pluripotent Stem Cells

Somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) by the ectopic expression of defined factors. iPSCs hold great promise for pharmaceutical screening and regenerative medicine but the mechanism of reprogramming is not well understood. This work examines a component process...

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Bibliographic Details
Main Author: Liu, Da
Other Authors: Wrana, Jeffrey
Language:en_ca
Published: 2014
Subjects:
MET
BMP
Online Access:http://hdl.handle.net/1807/44038