Serotonin- and Dopamine-mediated Neurotransmission in the Pathophysiology and Treatment of Parkinson’s Disease
Dopamine deficiency in the striatum is a central feature of Parkinson’s disease (PD). Symptomatic therapy with L-3,4-dihydroxyphenylalanine (L-DOPA) aims at restoring physiological dopaminergic neurotransmission within the brain. Unfortunately, current treatment paradigms fail to achieve this goal,...
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| Language: | en |
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2012
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| Online Access: | http://hdl.handle.net/1807/44077 |