Asymmetric Division of Damaged Proteins in Proliferating Cells

This thesis explores the unequal partitioning of damaged proteins during mitosis and its implications for cell fate. Initially described in unicellular organisms, it was unclear if this method was used in vivo in multicellular organisms and had functional consequences in mammalian cells. To determin...

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Bibliographic Details
Main Author: Bufalino, Mary Rose
Other Authors: van der Kooy, Derek
Language:en_ca
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/1807/44097