Uncovering the Functional Implications of Mu- and Delta-opioid Receptor Heteromerization in the Brain

Uncovering the Functional Implications of Mu- and Delta-opioid Receptor Heteromerization in the Brain

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Opioid Receptors (ORs) are involved in the pathophysiology of several neuropsychiatric conditions yet remain an untapped therapeutic resource. Although only mu-, delta-, and kappa-OR types have been cloned, additional subtypes result from complexes generated by direct receptor-receptor interactions...

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Bibliographic Details
Main Author: Kabli, Noufissa
Other Authors: George, Susan R.
Language:en_ca
Published: 2013
Subjects:
mu opioid receptor
delta opioid receptor
heteromer
depression
anxiety
brain
chronic morphine
G protein coupled receptor
mood
binding
internalization
interaction
0419
0317
Online Access:http://hdl.handle.net/1807/65509

Internet

http://hdl.handle.net/1807/65509

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