Investigating the Role of Deoxyhypusine Synthase in the Invasiveness of PC3 Cells Using siRNA
Deoxyhypusine synthase (DHS) catalyzes the first step in the hypusination of eukaryotic translation initiation factor 5A (eIF5A). In human cells, two eIF5A isoforms are present, eIF5A-1 and eIF5A-2, and DHS catalyzes the hypusination of both. Since both eIF5As are substrates for DHS, the biological...
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| Language: | en |
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2008
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| Online Access: | http://hdl.handle.net/10012/3842 |