??-Dystroglycan is essential for the induction of Egr3, a transcription factor important in muscle spindle formation
Muscle spindle fibers are specialized stretch receptors that allow the perception and coordination of limb movement. Differentiation of muscle spindles is initiated by signals derived from the in growing Ia sensory neurons during development. The sensory neuron secretes neuregulin which binds and si...
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| Language: | en |
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2009
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| Online Access: | http://hdl.handle.net/10012/4814 |