Characterization of p53 in rainbow trout cell lines

The tumour suppressor protein p53 is a critical protein in the DNA damage checkpoint pathway. It acts as a transcription factor that is involved in initiating the apoptotic pathway; disruption of this pathway can lead to various forms of cancer. Due to its importance in cancer prevention, p53 has be...

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Bibliographic Details
Main Author: Liu, Michelle
Language:en
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10012/5510