Suppressor analysis of the clk-1 mutants of Caenorhabditis elegans

clk-1 encodes a hydroxylase that is necessary for ubiquinone (UQ) biosynthesis. clk-1 mutants do not synthesize UQ, but instead accumulate the precursor demethoxyubiquinone (DMQ). When fed on bacteria that synthesize UQ the mutants are viable but display slow development, behaviours and aging. Howev...

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Bibliographic Details
Main Author: Branicky, Robyn.
Format: Others
Language:en
Published: McGill University 2006
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=100328