Studies of aging, metabolism and the age-dependent disease atherosclerosis in mouse mutants with altered mitochondrial function
Mutational disruption of the genes clk-1 and isp-1, the products of which are involved in mitochondrial oxidative phosphorylation, has been shown to extend lifespan in the nematode worm Caenorhabditis elegans. Here, we describe efforts to characterize the effects of disrupting the mammalian homologu...
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| Format: | Others |
| Language: | en |
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McGill University
2011
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103572 |