Gestational diethylstilbestrol impacts adult progeny heart structure, function and gene expression in mice
Diethylstilbestrol (DES), a potent endocrine disruptor, alters the physiologic function of endogenous steroid hormones. Moreover, the fetus is highly susceptible to epigenetic reprogramming and thus DES exposure in utero is thought to cause epigenetic changes by altering the methylation status of Cp...
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Language: | en |
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McGill University
2011
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=104818 |