The role of natural killer cell receptors in the control of natural killer cell functions

Natural killer (NK) cells possess the ability to destroy abnormal cells such as cancerous and virally-infected cells. A common feature of these cells is the downregulation of class I MHC molecules in an attempt to evade recognition by CD8+ T lymphocytes. "Missing-self" recognition allows N...

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Bibliographic Details
Main Author: Bélanger, Simon
Other Authors: Andrew Makrigiannis (Internal/Supervisor)
Format: Others
Language:en
Published: McGill University 2012
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=107643