Quantitative detection of N7-and O6-methylguanine adducts by liquid chromatography and mass spectrometry in brain tumour tissues from patients treated with temozolomide
Temozolomide (TMZ) is a DNA methylating agent currently used for the treatment of several types of glial tumours, including glioblastomas (GBM). While improved patient response has been observed with concomitant TMZ and radiotherapy followed by adjuvant TMZ treatment following surgical resection in...
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| Format: | Others |
| Language: | en |
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McGill University
2012
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110621 |