Studies on bisphosphonate elution from orthopaedic implants
In a 6-week rat model it was demonstrated that a small dose of peri-implant zoledronic acid (ZA) increased local bone formation 3-fold compared with controls. Ancillary in vitro studies using 14C-labeled ZA implant doses demonstrated biphasic elution profiles for implants coated with hydroxyapatite;...
Main Author: | |
---|---|
Format: | Others |
Language: | en |
Published: |
McGill University
2008
|
Subjects: | |
Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112582 |