A Src-Abl kinase inhibitor, SKI-606, blocks breast cancer invasion, growth and metastasis in vitro and in vivo /

A Src-Abl kinase inhibitor, SKI-606, blocks breast cancer invasion, growth and metastasis in vitro and in vivo /

The central role of Src in the development of several malignancies including breast cancer and the accumulating evidence of its interaction with receptor tyrosine kinases (RTK), integrins and steroid receptors have identified it as an attractive therapeutic target. In the current study we have evalu...

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Bibliographic Details
Main Author: Jallal, Houda.
Format: Others
Language:en
Published: McGill University 2007
Subjects:
Breast Neoplasms > drug therapy.
Neoplasm Invasiveness.
Neoplasm Metastasis.
Proto-Oncogene Proteins c-abl > antagonists & inhibitors.
src-Family Kinases > antagonists & inhibitors.
Aniline Compounds > pharmacology.
Nitriles > pharmacology.
Quinolines > pharmacology.
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112641

Internet

http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112641

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