Interplay of Mye and Max with Epigenetic Regulator Bmi1
The polycomb group protein Bmi1 is an epigenetic regulator essential for the proliferation of many types of cancers. By impeding the expression of the tumor suppressor p53, Bmi1 is able to prevent apoptosis and senescence. c-Myc, a prominent oncogene, cooperates with Bmi1 to stimulate cellular trans...
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Format: | Others |
Language: | en |
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McGill University
2013
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114264 |