Interplay of Mye and Max with Epigenetic Regulator Bmi1

The polycomb group protein Bmi1 is an epigenetic regulator essential for the proliferation of many types of cancers. By impeding the expression of the tumor suppressor p53, Bmi1 is able to prevent apoptosis and senescence. c-Myc, a prominent oncogene, cooperates with Bmi1 to stimulate cellular trans...

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Bibliographic Details
Main Author: Gocevski, Goran
Other Authors: Xiang-Jiao Yang (Supervisor)
Format: Others
Language:en
Published: McGill University 2013
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114264