Metabolic regulation via a nuclear receptor/miRNA Pathway

Cancer cell metabolism is often characterized by a shift from an oxidative to a glycolytic bioenergetic pathway, a phenomenon known as the Warburg effect. miR-378* is embedded within PPARGC1b which encodes PGC-1beta, a transcriptional regulator of oxidative energy metabolism. We show that miR-378* a...

Full description

Bibliographic Details
Main Author: Eichner, Lillian
Other Authors: Vincent Giguere (Supervisor)
Format: Others
Language:en
Published: McGill University 2013
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114320