Analysis of candidate regulators of TBC-2 and endosome maturation in «Caenorhabditis elegans»
The Rab5 and Rab7 GTPases are key regulators of endosome to lysosome trafficking, whose activities are positively regulated by Rab Guanine nucleotide Exchange Factors and negatively regulated by GTPase Activating Proteins (GAP). In this thesis, the nematode Caenorhabditis elegans was used as a model...
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| Format: | Others |
| Language: | en |
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McGill University
2013
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114348 |