Maintaining calcium homeostasis in a primary culture model of amyotrophic lateral sclerosis
Calcium dyshomeostasis has been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). Limiting calcium entry into motor neurons, the ultimate cell-type that is lost in ALS, has been shown to protect these cells from ALS-causing mutant superoxide dismutase 1 (SOD1) toxicity. Lomerizi...
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| Format: | Others |
| Language: | en |
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McGill University
2013
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114440 |