Mechanisms of dopamine toxicity in oligodendrocytes

Mechanisms of dopamine toxicity in oligodendrocytes

Oligodendrocyte progenitors are highly sensitive to oxidative insults. Among the factors postulated to contribute to this susceptibility are high levels of intracellular iron and low antioxidant content. During ischemia, the neurotransmitter dopamine (DA) is released and may contribute to oxidative...

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Bibliographic Details
Main Author: Hemdan, Sandy, 1977-
Format: Others
Language:en
Published: McGill University 2008
Subjects:
Oligodendroglia > metabolism.
Dopamine > toxicity.
HSP90 Heat-Shock Proteins > antagonists & inhibitors.
Proto-Oncogene Proteins c-akt > antagonists & inhibitors.
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115686

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http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115686

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