Synthesis and biological evaluation of 2- aminothiophene and benzothiazole derivatives as isoprenoid biosynthesis inhibitors
The condensation of stable 2-(1-(trimethylsilyl)ethylidene)malononitrile with elemental sulfur was explored in the parallel-synthesis of a small library of structurallydiverse2-aminothiophenesandthieno[2,3-d]pyrimidines. Bromination and ipso-iododesilylation of these heterocyclic scaffolds provided...
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| Format: | Others |
| Language: | en |
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McGill University
2013
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=117127 |