Targeting antibiotic resistance through a versatile pantetheine scaffold: pantetheine derivatives as AAC(6')-Ii resistance inhibitors and novel pantothenamide antibacterial agents
Aminoglycosides are broad-spectrum antibiotics used in the treatment of serious infections. With the rapid emergence and spread of antibiotic resistance, their therapeutic use is becoming increasingly threatened. The most common mechanism of aminoglycoside resistance is the expression of aminoglycos...
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| Format: | Others |
| Language: | en |
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McGill University
2013
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119452 |