Prodrug inhibitors of the aminoglycoside resistance-causing enzyme aminoglycoside N-6'-acetyltransferase

Aminoglycosides are a class of broad-spectrum antibiotics that first came to prominence in the 1950s as the first effective treatment for tuberculosis. Aminoglycoside resistance in bacteria, however, is increasingly becoming a difficult problem to treat. One of the most common mechanisms of aminogly...

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Bibliographic Details
Main Author: Vong, Kenward
Other Authors: Karine Auclair (Supervisor)
Format: Others
Language:en
Published: McGill University 2013
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119511