Mechanisms of action of the novel anti-cancer organic arsenical darinaparsin (ZIO-101, S-dimethylarsino- glutathione, Dar) in cancer cells
Arsenic trioxide (ATO) is a successful treatment option for Acute Promyelocytic Leukemia (APL), but other cancers remain mildly sensitive to ATO at clinically achievable doses. Moreover, APL cells can develop resistance to ATO. It has been shown that resistance to ATO and/or moderate sensitivity cor...
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| Format: | Others |
| Language: | en |
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McGill University
2013
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119553 |