Capicua regulates proliferation and survival of RB- deficient cells

The retinoblastoma tumour suppressor, Rb, is a cell cycle regulator that acts to prevent the progression from G1 to S-phase. Rb regulates this transition by inhibiting E2F family transcription factors which control the expression of genes required for the G1 –S phase progression. Consequently, mutat...

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Bibliographic Details
Main Author: Krivy, Kate
Other Authors: Nam Sung Moon (Internal/Supervisor)
Format: Others
Language:en
Published: McGill University 2014
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121335