Capicua regulates proliferation and survival of RB- deficient cells
The retinoblastoma tumour suppressor, Rb, is a cell cycle regulator that acts to prevent the progression from G1 to S-phase. Rb regulates this transition by inhibiting E2F family transcription factors which control the expression of genes required for the G1 –S phase progression. Consequently, mutat...
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| Format: | Others |
| Language: | en |
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McGill University
2014
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121335 |