Prion protein topologies and the effect on its neuroprotective function
The normal prion protein (PrP) is ubiquitously expressed and is especially abundant in the brain. However, the major physiological function of PrP has remained elusive. Recently, it was demonstrated that PrP prevents Bcl-2 associated protein X (Bax)-mediated cell death by inhibiting the initial Ba...
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| Format: | Others |
| Language: | en |
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McGill University
2008
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18773 |