Identification and molecular genetic characterization of a coq-4 knockout mutation in Caenorhabditis elegans
In Caenorhabditis elegans, mutations in the clk-1 gene result in delayed embryonic and post-embryonic development, a slowing down of rhythmic behaviors and an extended life span. CLK-1 encodes the demethoxyubiquinone (DMQ or DMQn) hydroxylase in the ubiquinone (CoQ or Qn) biosynthesis pathway. Thus,...
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Language: | en |
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McGill University
2001
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33769 |