Enzyme substitution therapy for hyperphenylalaninemia with phenylalanine ammonia lyase : an alternative to low phenylalanine dietaty treatment : effective in mouse models

Enzyme substitution therapy for hyperphenylalaninemia with phenylalanine ammonia lyase : an alternative to low phenylalanine dietaty treatment : effective in mouse models

Phenylketonuria (PKU) and related forms of non-PKU hyperphenylalaninemias (HPA) result from deficiencies in phenylalanine hydroxylase (PAH), the hepatic enzyme that catalyses the conversion of phenylalanine (phe) to tyrosine (tyr). Patients are characterised by a metabolic phenotype comprising eleva...

Full description

Bibliographic Details
Main Author: Sarkissian, Christineh N.
Other Authors: Scriver, C. R. (advisor)
Format: Others
Language:en
Published: McGill University 2000
Subjects:
Phenylalanine > Metabolism > Disorders > Treatment.
Phenylketonuria > Treatment.
Lyases.
Phenylalanine Ammonia-Lyase.
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37832

Internet

http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37832

Similar Items