Targeting focal adhesion signaling in cancer and acquired resistance to focal adhesion kinase inhibitors

In cancer progression, the development of metastases is characteristic of late stage disease and makes treatment and cure more difficult. In order for metastasis to occur, cancer cells must gain motile and invasive phenotypes. As one of the keystone proteins involved in cell motility and invasion, F...

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Bibliographic Details
Main Author: Lougheed, Caroline
Other Authors: Moulay A Alaoui-Jamali (Supervisor)
Format: Others
Language:en
Published: McGill University 2010
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=94996