Mechanisms of demyelination and axonal damage in a CD8+ T cell-mediated model of spontaneous demyelinating disease

Autoimmune demyelinating diseases of the nervous system are a major cause for neurological impairment in humans. Recent evidence indicates that CD8+ T cells may contribute significantly to pathogenesis in these conditions but the mechanisms by which CD8+ T cells induce damage remain to be establishe...

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Bibliographic Details
Main Author: Estrada Guadarrama, José
Other Authors: Sylvie Fournier (Internal/Supervisor)
Format: Others
Language:en
Published: McGill University 2010
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95097