The eIF2alpha phosphorylation pathway as a novel component of PI3K signaling with implications in tumor treatment
Inhibition of protein synthesis by phosphorylation of eIF2alpha on serine 51 is mediated by a family of kinases activated by various forms of stress. The biological outcome of eIF2alpha phosphorylation can either be cytoprotective or pro-apoptotic. Translation is also regulated at the initiation ste...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | en |
| Published: |
McGill University
2011
|
| Subjects: | |
| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=96719 |