Characterization of the interaction between the adaptor protein Nck and the protein kinase PKR

Tight regulation of the double-stranded RNA (dsRNA)-activated protein kinase (PKR) is critical for the maintenance of cellular homeostasis due to its potent inhibitory role on general translation. Previously, we have identified the adaptor protein Nck-1 as a novel cellular regulator of PKR activatio...

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Bibliographic Details
Main Author: Abu-Thuraia, Afnan
Other Authors: Louise Larose (Supervisor)
Format: Others
Language:en
Published: McGill University 2011
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=96908