Parkin interacts with the 26S proteasome via Rpn13, a novel ubiquitin receptor
Mutations in the Parkin gene cause a juvenile-onset for of Parkinson's disease (PD) that is transmitted in an autosomal recessive way. Studies have shown that mutations in parkin account for almost 50% of all juvenile-onset forms of PD, making parkin one of the most studied genes as a causative...
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| Format: | Others |
| Language: | en |
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McGill University
2011
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97128 |