A curated database and probabilistic model of endoplasmic reticulum quality control /

The folding and assembly of proteins in the endoplasmic reticulum (ER) lumen and membrane are monitored by ER quality control (ERQC) mechanisms. This thesis focuses on two elements of ERQC: the unfolded protein response (UPR) and ER-associated degradation (ERAD), essential processes that prevent the...

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Bibliographic Details
Main Author: Calafell, Sara J.
Format: Others
Language:en
Published: McGill University 2005
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97917