Role of EFNBs and EphB4 in T cell development and function

Role of EFNBs and EphB4 in T cell development and function

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Eph kinases are the largest family of cell surface receptor tyrosine kinases. The ligands of Ephs, ephrins (EFNs), are also cell surface molecules. Ephs interact with EFNs and the receptors and ligands transmit signals in both directions, i.e., from Ephs to EFNs and from EFNs to Ephs. Ephs and EFNs...

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Bibliographic Details
Main Author: Jin, Wei
Other Authors: Wu, Jiangping
Language:en
Published: 2014
Subjects:
Eph
EFNB
Conditional gene knockout
T cell development
T cell function
IL-7Ra
Thymic epithelial cells
IL-7Rα
cellules épithéliales Thymique médullaire (mTEC)
Délétion génique conditionnelle
Développementdes cellules T
Fonction des cellules T
Health Sciences - Immunology / Sciences de la santé - Immunologie (UMI : 0982)
Online Access:http://hdl.handle.net/1866/10499

Internet

http://hdl.handle.net/1866/10499

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