Role of Retrotransposons as a Major Source of Intra- and Inter-Individual Epigenetic Variations in the Mammalian Genome

Transcription of retrotransposons is usually repressed by DNA methylation, but a few elements partially escape this repression mechanism. I used two approaches as my dissertation study to identify unmethylated intracisternal A-particles (IAPs) and also to understand why some of IAPs escape DNA methy...

Full description

Bibliographic Details
Main Author: Ekram, Muhammad Badre
Other Authors: DiMario, Patrick Joseph
Format: Others
Language:en
Published: LSU 2013
Subjects:
Online Access:http://etd.lsu.edu/docs/available/etd-04022013-204739/