RNAi Knockdown of Nopp140 Induces the Minute Syndrome in Drosophila: A Potential Model for the Human Treacher Collins Syndrome
Nopp140 is believed to play a chaperone function in pre-rRNA processing and ribosome assembly. Alternative splicing in Drosophila may yield two isoforms: the first, Nopp140-True, shares a conserved carboxy terminus with human Nopp140. The second contains a distinctive glycine and arginine rich (RGG)...
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| Format: | Others |
| Language: | en |
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LSU
2006
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| Online Access: | http://etd.lsu.edu/docs/available/etd-05262006-013154/ |