Transmembrane Signaling and Conformational Regulation of Integrin
Integrins are heterodimeric cell adhesion molecules that play an essential role in hemostasis, thrombosis, cell migration, and can transmit bidirectional signals. The inside-out activating signal triggers integrin conformational change, leading to high affinity for extracellular ligands. Binding of...
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Format: | Others |
Language: | en |
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LSU
2015
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Online Access: | http://etd.lsu.edu/docs/available/etd-06262015-172631/ |