Transmembrane Signaling and Conformational Regulation of Integrin

Integrins are heterodimeric cell adhesion molecules that play an essential role in hemostasis, thrombosis, cell migration, and can transmit bidirectional signals. The inside-out activating signal triggers integrin conformational change, leading to high affinity for extracellular ligands. Binding of...

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Bibliographic Details
Main Author: Hu, Ping
Other Authors: Garno, Jayne
Format: Others
Language:en
Published: LSU 2015
Subjects:
Online Access:http://etd.lsu.edu/docs/available/etd-06262015-172631/