Design, Synthesis, and Antibacterial Properties of Dual-Ligand Inhibitors of Acetyl-CoA Carboxylase and Mechanism of Action for the Antibacterial Agent Moiramide B
An urgent demand for the development of new antibiotics has been created by the increase in clinical cases involving drug-resistant pathogenic bacteria. A novel target for antibacterial development is acetyl-CoA carboxylase, a multifunctional enzyme that catalyzes the first committed step in fatty a...
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| Format: | Others |
| Language: | en |
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LSU
2014
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| Online Access: | http://etd.lsu.edu/docs/available/etd-09112014-145620/ |