Silver Nanoparticle Oligonucleotide Conjugate For Targeted Gene Silencing
This project explored a gene-regulated chemotherapy using a silver nanoparticle (SNP) conjugated with deoxyribozyme (DNAzyme) oligonucleotides which target a mutated gene in select cancer cells, sensitize them to doxorubicin treatment. Light exposure to the SNP-DNAzyme conjugates disengages the olig...
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| Format: | Others |
| Language: | en |
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LSU
2014
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| Online Access: | http://etd.lsu.edu/docs/available/etd-11152014-131055/ |