Insights into the Development of Chemotherapeutics Targeting PFKFB Enzymes
The PFKFB enzymes control the primary checkpoint in the glycolytic pathway and are implicated in a multitude of diseases: from cancer, to schizophrenia, to diabetes, and heart disease. The inducible isoform, PFKFB3, is known to be associated with the upregulation of glycolysis in many cancers. The f...
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| Format: | Others |
| Language: | en |
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LSU
2015
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| Online Access: | http://etd.lsu.edu/docs/available/etd-11162015-154823/ |