Structure-activity studies of bioreductive anti-cancer agents
Bioreductive agents are an important class of anti-cancer drugs. The role of functional groups in modulating bioreductive drug activation by either DT-diaphorase or NADPH:cytochrome P-450 reductase was studied. 2-(Di(chloroethyl)amino)-1,4-benzoquinone, BM was used as a model bioreductive. Three ana...
| Main Author: | |
|---|---|
| Language: | en_US |
| Published: |
2007
|
| Online Access: | http://hdl.handle.net/1993/1325 |