Regulation of a prion-induced immune response by miRNA-146a

Prion diseases are curious neurodegenerative diseases characterized by the conversion of a cellular protein, PrPC, into an infectious isoform, PrPSc. One of the earliest hallmarks of disease and concurrent with prion deposition, is the activation of the brain’s principal immune effector cells, micro...

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Bibliographic Details
Main Author: Gushue, Shantel
Other Authors: Booth, Stephanie (Medical Microbiology)
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/1993/24032